施工実績

Trend for the serum uric acid profile across the quintiles out of consumption have been analyzed into the linear regression patterns utilising the median opinions of per quintile to reduce the latest determine away from outliers. elizabeth., gel uric-acid >eight.0 milligrams/dl for males and you may >5.7 milligrams/dl for women ) changing for the very same covariates.

Overall performance

The suggest age the study populace is actually forty-five decades. The mean serum uric acid top is 5.32 milligrams/dl (six.07 mg/dl one of males and you will cuatro.65 mg/dl certainly one of girls), and you may 18% got hyperuricemia (19% certainly one of men and 17% one of people). The fresh suggest gel uric acid membership was comparable across the race/ethnicity kinds (we.e., white, African american, Mexican American, or other). The features predicated on consumption off purine-rich restaurants teams, dairy foods, and you will full healthy protein are offered inside the Desk 1. Having growing consumption from chicken, the age had a tendency to decrease, the fresh proportion of men increased, and you will everyday alcohol intake a little enhanced. Blood circulation pressure tended to feel less frequent that have broadening consumption of beef and you will dairy food.

We explored potential interactions by sex, BMI (<25 kg/m 2 versus ?25 kg/m 2 ), and alcohol use (abstainer versus drinker) by testing the significance of interaction terms added to our final multivariate models

• * Except in which shown or even, opinions will be the imply. Bmi = bmi.
• † Allopurinol and uricosuric agents.
• ‡ Energy-adjusted. Opinions have been in grams daily.

The serum uric acid level increased with increasing total meat or seafood intake (Table 2). After adjusting for age, the serum uric acid level in the highest quintile group of total meat intake was higher than that in the lowest quintile by 0.48 mg/dl (95% CI 0.34, 0.61; P < 0.001 for trend). The corresponding difference for seafood was 0.16 mg/dl and (95% CI 0.06, 0.27; P = 0.005 for trend). After adjusting for other covariates, these differences between the extreme quintiles were attenuated but remained significant (P < 0.05 for both comparisons) (Table 2).

We explored potential interactions by sex, BMI (<25 kg/m 2 versus ?25 kg/m 2 ), and alcohol use (abstainer versus drinker) by testing the significance of interaction terms added to our final multivariate models

• * Thinking come in milligrams/dl. 95% CI = 95% confidence period.
• † Variations for every single additional everyday providing try demonstrated to have full beef and dairy food. Variation for each a lot more per week serving are exhibited to own seafood in check so you can mirror the shipping . Differences for each and every extra daily 5% of time are displayed getting full healthy protein.
• ‡ Modified to have age, gender, total opportunity intake, body mass index, usage of diuretics, ?-blockers, allopurinol, and you may uricosuric agents, self-statement away from blood circulation pressure and you will gout, solution creatinine height, and you may intake away from liquor, overall meats, seafood, and you can dairy products.
• § Modified to possess age, intercourse, overall energy intake, body mass index, the means to access diuretics, ?-blockers, allopurinol, and you can uricosuric representatives, self-report of hypertension and you may gout, serum creatinine peak, and you will intake out of alcoholic drinks and you may complete body weight (% of your energy).

Regarding the ages-adjusted research to have individual beef facts, the distinctions in gel the crystals profile between the tall quintiles out-of consumption had been 0.forty five milligrams/dl (95% CI 0.33, 0.56) to possess beef, 0.twenty-seven milligrams/dl (95% CI 0.18, 0.35) for pork, and you can 0.forty-eight mg/dl (95% CI 0.34, 0.61) to have canned meats. These magnitudes was attenuated, however, stayed extreme, once multivariate adjustment (Desk step three). Likewise, large consumption off private seafood items try of this advanced of solution the crystals (Table step 3).

We explored potential interactions by sex, BMI (<25 kg/m 2 versus ?25 kg/m 2 ), and alcohol use (abstainer versus drinker) by testing the significance of interaction terms added to our final multivariate models

• * An average day-after-day consumption to have personal edibles try categorized with the quintiles of intake as much as possible (i.elizabeth., chicken, pork and you will ham, processed meats, and you will poultry). When the small stratum sized personal a meal don’t succeed quintile research (we.age., the liver and you can body organ meat, fish, almost every other seafood, dairy, yoghurt, and you may parmesan cheese), we used the following kinds of mean portions daily: 0, 0.01–0.09, 0.1–0.forty-two, 0.5–0.99, and you can ?step 1.0. Canned chicken means bacon, sausage (chorizo), hot pet, salami, and you can bologna. Almost every other fish represents shrimp, clam, crab, lobster, and you may oyster. Solution uric acid philosophy have milligrams/dl. 95% CI = 95% confidence interval.